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Carboxymethyl Chitosan

CAS NO.: 83512-85-0
Carboxymethyl chitosan is a water-soluble derivative of chitosan. The introduction of carboxymethyl makes it an amphoteric polyelectrolyte containing both amino and carboxyl groups, which destroys the original crystal structure of chitosan, improves its solubility adaptability, and has good biocompatibility and biodegradability.
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Quick Details

Name

Carboxymethyl Chitosan

CAS NO.

83512-85-0

Molecular Formula

(C6H11NO4)m(C2H2O2)n

Appearance

White to light brown powder

Classification

Pharma Grade


Molecular Structuer


Product Introduction

Carboxymethyl chitosan is a water-soluble chitosan derivative with many properties, such as strong antibacterial properties, preservation effects, and amphoteric polyelectrolytes. It has many applications in cosmetics, preservation, medicine, etc., and is also one of the chitosan biomaterials that has been studied more in recent years. Carboxymethyl chitosan is a chemical synthetic product that has appeared in recent years. It has important significance in medicine, chemical industry, environmental protection, and health products. Its stable properties and pharmacological effects such as antibacterial and anti-infection, lipid-lowering and prevention of arteriosclerosis are destined to play a greater role in human daily life in the future.


Product Efficacy & Application

● Water solubility

Due to the introduction of carboxyl groups into chitosan molecules, the regularity of its crystals is destroyed, which greatly reduces the crystallinity. In addition, the introduction of hydrophilic groups significantly improves the water solubility of carboxymethyl chitosan compared with chitosan, and the water solubility increases with the increase of the degree of substitution of carboxyl groups. It can be dissolved in a wider pH range, and its application range is also expanded.

● Antibacterial property

Carboxymethyl chitosan has good antibacterial activity and has inhibitory effects on common food spoilage bacteria such as Staphylococcus aureus, Escherichia coli, and Bacillus subtilis. The minimum inhibitory concentration for Staphylococcus aureus is 0.1%, and the minimum inhibitory concentration for Escherichia coli and Bacillus subtilis is 0.2%.

● Film-forming property

Carboxymethyl chitosan has good film-forming property, and the film formed is smooth, transparent, flexible and breathable. Carboxymethyl chitosan aqueous solution can form a film at a mass fraction of 0.2%. As the concentration of the aqueous solution increases, the toughness of the film increases, the thickness increases, but the transparency decreases, and the color turns yellow; when the mass fraction of carboxymethyl chitosan is about 1%, the film-forming effect is the best.

● Adsorption performance

Chitosan is a natural biosorbent with good performance. It has a strong adsorption capacity for many metal ions and can be used to remove various toxic metal ions. Carboxymethyl chitosan molecules contain -OH, -NH2, -COOH and other groups. Compared with chitosan, it can more effectively complex metal ions.

● Hygroscopicity and moisture retention

Carboxymethyl chitosan contains a large number of amino and hydroxyl groups in its molecular structure. In addition, carboxymethyl groups are introduced, which can combine with water to form hydrogen bonds. Therefore, carboxymethyl chitosan exhibits good hygroscopicity and moisture retention. The hygroscopicity of 0.25% carboxymethyl chitosan solution is equivalent to that of 20% propylene glycol. The weighing method can be used to examine the hygroscopicity and moisture retention of chitosan and its derivatives.

● Others like carboxymethyl chitosan also has antioxidant, anti-tumor, chondrocyte growth promotion and hemostatic effects.


Product Specification

Test standard

Enterprise Standard

ITEMS

Criteria

Appearance

White to light brown powder.

Clarity of solution

Solution clarification.

pH

6.0~10.0

Degree of carboxylation

≥80%

Viscosity

≤100mpa.s

Loss on drying

≤10.0%

Heavy metal

≤10ppm

Packaging and storage

Keep out of light and tightly sealed


Packing & Storage

● Internal packing: packed with PE bag+aluminum foil bag.

● Outer packing: packed in drum.

● Storage: keep out of light and tightly sealed.

● Label: regular labels or customized.

● Packing: 10g/bag, 50g/bag, 100g/bag, 1kg/bag, 10kg/bag/drum

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